Wednesday, 18 January 2017

Even small amount of daily activity can boost colon cancer survival

A new U.S. study conducted on 1,200 colon cancer patients indicated a 19% decrease in early risk of death for those exercising 30 minutes or more on a daily basis. Further, individuals who exercised at least 5 hours per week saw their survival rate rise to 25%.  According to Dr. Andrew Chan, associate professor of medicine at Harvard Medical School, these findings do support the notion that "patients who have cancer and who are physically active...have a better prognosis."

To read more about this study, click here.

Friday, 13 January 2017

Chemo Brain may last for several months after breast cancer treatment

A new study conducted in the United States, considered to be the largest of its kind to date, explored explored the effects of memory and attention issues affecting breast cancer survivors after undergoing chemotherapy treatment.  According to study author Michelle Janelsins, assistant professor o surgery, radiation oncology and neuroscience at the University of Rochester Medical Center and the Wilmot Cancer Institute in New York, "a month after chemo ended, 45% of patients reported a significant decline in so-called cognitive abilities", an effect that continued to linger 6 months later where "36% of patients still felt their mental ability had declined."

To read more about this study, click here.

Friday, 6 January 2017

Drug for advanced bone cancer may require less frequent dosing

Researchers at the Helen F. Graham Cancer Center & Research Institute in Newark, Delaware have determined that use of Zometa, a drug used to treat bone cancer, reduces side effects in patients and increases cost savings wen administered every 3 months instead of monthly.  This change in dosage has not resulted in increased risk of bone problems over a 2-year period.  The study, conducted on more than 1800 patients with breast cancer, prostate cancer, or multiple myeloma indicated bone problems in 30% of patients who received the drug monthly compared to 29% who were administered the drug every 3 months.

To read more about this study, click here.

Tuesday, 3 January 2017

New targeted therapies show promise for treating advanced GIST

Two early-phase clinical trials testing new targeted therapies for advanced gastrointestinal stromal tumors (GIST) have produced promising preliminary results. Although the findings are preliminary, Lee Helman, M.D., of NCI's Center for Cancer Research, said the drugs show substantial promise as a treatment for patients with GIST whose tumors stop responding to standard therapies.

The trial results were presented earlier this month at the EORTC-NCI-AACR Molecular Targets and Cancer Therapeutics ConferenceExit Disclaimer in Munich.

Read more here.

Response to Durvalumab increased with high PD-L1 expression in pretreated NSCLC

Durvalumab treatment in the second-line setting or beyond demonstrated clinical benefit and led to durable responses in heavily pretreated patients with locally advanced or metastatic non-small cell lung cancer (NSCLC), according to findings presented at the 17th World Lung Cancer Conference in Vienna.

Rad more here.

Monday, 19 December 2016

MEK inhibitor/Taxane combination active in triple-negative breast cancer

A small clinical trial demonstrated encouraging clinical activity in triple-negative breast cancer (TNBC) treated with a MEK inhibitor and a taxane. The combination of cobimetinib (Cotellic) and paclitaxel led to confirmed partial responses in 6 of 16 patients and 2 additional unconfirmed partial responses. Five of the 6 confirmed responses proved to be durable, persisting for about 20 weeks. “This is the first study to evaluate the combination of cobimetinib and paclitaxel in triple-negative breast cancer,” Adam M. Brufsky, MD, PhD, associate chief of hematology oncology, and co-director of the Comprehensive Breast Cancer Center at the University of Pittsburgh Medical Center, and colleagues concluded in a presentation at the 2016 San Antonio Breast Cancer Symposium. “The safety profile of combined cobimetinib and paclitaxel is manageable and consistent with the known safety profiles for each drug.

- See more here.

SABCS 2016: Menopausal symptoms affect adherence with Tamoxifen but also with placebo

Although menopausal symptoms play a role in adherence to tamoxifen, the strength of the association between menopausal symptoms and adherence was similar in women assigned to placebo and those assigned to tamoxifen during a large, placebo-controlled trial by investigators from the United Kingdom and Australia.

Read more here.

Monday, 12 December 2016

Strength training may prevent side effect of breast cancer surgery

New research conducted at Florida State University in Tallahassee suggests that strength training may be beneficial for breast cancer survivors who have had surgery.  The study, conducted on 27 breast cancer survivors who underwent supervised moderate-intensity strength workouts shows that "weightlifting appeared to help prevent swelling in the arms and chest, a common side effect of breast cancer treatment."

To read more about this study, click here.

Friday, 9 December 2016

Therapeutic vaccine promising for leukemia

New research arising from the Cancer Vaccine Program at the Beth Israel Deaconness Medical Center in Boston  indicates that an anti-cancer vaccine derived from an acute myeloid leukemia patient's cells significantly increases the chance of long-term survival.

According to senior researcher Dr. David Avigan, "the vaccine has produced long-term remission for 70% of a small group of vaccinated patients with an average age of 63."

To read more about this study, click here.

Friday, 2 December 2016

Cancer survivors at increased risk of severe heart attack

A new study conducted at the Mayo Clinic in Rochester, Minnesota indicates that cancer survivors are at increased risk of suffering a severe heart attack.  According to cardiologist and study senior author Dr. Joerg Herrmann, the study, conducted on 2,300 heart attack patients found that 10% were cancer survivors.  While not all of these heart attacks were fatal, a correlation was indicated, as "patients with a history of cancer were more likely to arrive at the hospital with cardiogenic shock, where the heart suddenly can't pump enough blood,"

To read more about this study, click here.